Expression of hematopoietic surface makers in E8-10d yolk sac cells.

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Expression of hematopoietic surface makers in E8-10d yolk sac cells.

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2014-12-01

De novo generation of macrophage from placenta-derived hemogenic endothelium

胚胎造血发育

单细胞转录组学

We profile the transcriptional landscape of mouse fetal placenta and identify four distinct types of haematopoietic stem/progenitor cells (HSPCs) during mid-gestation using single-cell RNA sequencing.

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In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis

胚胎造血发育

细胞谱系追踪

During embryogenesis, haematopoietic and endothelial lineages emerge closely in time and space. It is thought that the first blood and endothelium derive from a common clonal ancestor, the haemangiobl

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A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo. Mus musculus

胚胎造血发育

造血干细胞调控

Background: During mouse embryonic development, definitive hematopoiesis is first detected around embryonic day (E) 10.5 in the aorta-gonad-mesonephros (AGM) region. Hematopoietic stem cells (HSCs) ar

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RUNX1 and the endothelial origin of blood

胚胎造血发育

生血内皮细胞转录组

The transcription factor RUNX1 is required in the embryo for formation of the adult hematopoietic system. Here we describe the seminal findings that led to the discovery of RUNX1 and of its critical r

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RNA-Seq of sorted E10.5 and E11.5 AGM cell populations from Gata3-GFP embryos

胚胎造血发育

单细胞转录组学

The aim of this study was to examine the whole transcriptome of pools of 20 cells of Gata3-expressing AGM subpopulations (haematopoietic [HC], mesenchymal [MC], sympathetic nervous system [SNS], and e

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Expression of hematopoietic surface makers in E8-10d yolk sac cells.

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