RNA sequencing comparison of B7-H3.TMIGD2 and B7-H3.CD28.4-1BB CAR-T cells in vitro
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE254544
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CAR-T cell costimualtory domains can alter CAR-T cell phenotypes. We therefore performed RNA sequencing to understand the effect of TMIGD2 vs CD28.4-1BB comstimulation in B7-H3 CAR-T cells after in vitro coculture. We cocultured CAR-T cells and HCC827 tumor cells for 72 hours. After isolation of T cells and T cell RNA, we performed RNA sequencing
创建时间:
2024-05-08



