Crystal structure of JAK2 JH1 in complex with pacritinib
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Crystal structure of JAK2 JH1 in complex with pacritinib Descriptor: 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene, Tyrosine-protein kinase JAK2 Authors: Miao, Y, Haikarainen, T. Deposit date: 2022-11-18 Release date: 2023-11-29 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J.Med.Chem., 67, 2024
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2022-11-18
