Echocardiographic Measurements and Tissue Weight Ratios.

FS% fractional shortening, LVIDd left ventricular inner diameter at diastole, and Heart/Body heart weight to body weight ratio. Values are shown as predicted means with its 95% confidence interval. Groups are stratified by treatment and diet as follows: Normal Diet-Vehicle (n = 10), Normal Diet-Low Dose GGF2 (n = 9), Normal Diet-High Dose GGF2 (n = 9), Fatty Diet-Vehicle (n = 9), and Fatty Diet-High Dose GGF2 (n = 9). †FS % changes over time were analyzed using the generalized least squares linear regression method, and estimated means were fit using restricted maximum likelihood. Week 1 pre-treatment values were adjusted by adding a restricted cubic spline to the model. *Indicates significance with p‡LVIDd changes over time were also analyzed using GLS regression fit by REML, and week 1 pre-treatment values were adjusted by restricted cubic spline. No significant difference was found between groups at each time point. §Heart/Body weight ratios were analyzed using ordinary least squares and one-way ANOVA. Heart/Body weight ratio comparison was found to be non-significant between groups.