Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility (Mouse single cell RNA-Seq mESCs). Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility (Mouse single cell RNA-Seq mESCs)

We report a new technology for the parallel bimodal analysis of RNA-seq and ATAC-seq within a single-cell, known as ASTAR (Assay for Single-cell Transcriptome and Accessibility Regions). Overall design: ASTAR-RNAseq libraries were prepared from mESCs with inducible DUX ORF and 2c-GFP constructs