five

Expression data from mouse intestinal organoids I. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA308752
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资源简介:
APC inactivation is the early process in the tumorigenesis of colorectal cancer. We established organoid cultures from intestines of genetically modifeid mice harboring Apcfl/fl and R26CreERT2 allele We used microarrays to determine the alterations in intestinal stem cells in response to APC inactivation. Overall design: Organoids were treated with 4OHT to induce recombination of APC or left untreated, and collected at 4 or 6 days after treatment. RNA were extracted and hybridization on Affymetrix microarrays.
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2016-01-13
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