Human Protein Atlas - Structure

The Structure section contains information about the three-dimensional structure of human proteins.The predicted 3D structure from the AlphaFold Protein Structure Database project is shown together with experimentally determined structures from the Protein Data Bank (PDB). All antigens with known sequence has been mapped and can be displayed on the protein structures. Additionally the amino acid positions of population variants and variants with known clinical relevance in the Ensembl variation database can be shown. More information about the specific content and the generation and analysis of the data in the section can be found in the Methods Summary.
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the experimental and predicted 3D structure of proteins
the known missense variants with clinical significance
the known missense variants in the population
the antigen structure for the majority of the antibodies

结构部分包含了关于人类蛋白质三维结构的信息。AlphaFold蛋白质结构数据库项目预测的3D结构与蛋白质数据银行（PDB）中实验确定的构象并陈展示。所有已知序列的抗原均已进行映射，并可显示于蛋白质结构之上。此外，群体变异及在Ensembl变异数据库中已知具有临床相关性的变异的氨基酸位置亦得以呈现。关于本节具体内容以及数据的生成与分析方法的详细信息，可在方法概要中查得。了解以下内容：蛋白质的实验与预测三维结构、具有临床意义的已知错义变异、群体中的已知错义变异、大多数抗体的抗原结构。