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Changes in Gene expression mediated by Cyclic Mechanical Stress in Trabecular Meshwork Cells

ChEBI2009-03-04 更新2026-07-21 收录

小梁网细胞生物力学

青光眼病理

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-14768 数据链接链接失效反馈

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Changes in Gene expression mediated by Cyclic Mechanical Stress in Trabecular Meshwork Cells

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创建时间：

2009-03-04

青光眼病理

缺氧应激转录组学

Vascular hypoperfusion is a pathological phenomenon in the glaucomatous optic nerve head. We report transcriptional responses in GFAP-negative LC cells exposed to in-vitro hypoxic stress (1%O2). The s

NIAID Data Ecosystem70

Additional file 4 of Astrocytes of the optic nerve exhibit a region-specific and temporally distinct response to elevated intraocular pressure

青光眼病理

时间序列基因表达

Additional file 4: Supplementary Table 2. Differential expression analysis using a likelihood ratio test (LRT) focusing on genes in the ONH that differ over time (0, 7 and 30 days) in microbead inject

Figshare2023-11-22 更新60

Glis1 regulates gene expression in trabacular meshwork

眼小梁网基因调控

青光眼病理

Glis1 regulates the fuctional properties of trabacular meshwork via regulating the gene expression at transcriptional level. Overall design: Trabacular meshwork cells were knockdown and overexpressed

NIAID Data Ecosystem30

Human aqueous humor of Primary open angle glaucoma LC-MS/MS

蛋白质组学分析

青光眼病理

The main objective of this study was to adopt discovery based approach and define quantitative expression of human AH samples of glaucoma (N= 5) and non-glaucoma subjects (N=5) by using a state-of-the

NIAID Data Ecosystem60

Suprachiasmatic nucleus

青光眼病理

昼夜节律紊乱

Glaucoma is characterized by the progressive degeneration of retinal ganglion cells (RGCs) and damage to the optic nerve, with increased intraocular pressure (IOP) being one of the risk factors for th

Figshare2024-12-02 更新60

Changes in Gene expression mediated by Cyclic Mechanical Stress in Trabecular Meshwork Cells

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