Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability

Chromatin immuno-precipitation (ChIP) of Rad52-bound to ssDNA that was compatible with next-generation sequencing to map sites of DNA damage induced by accumulation of genomic DNA-RNA hybrids.本数据集为针对与单链DNA（ssDNA）结合的Rad52的、可适配下一代测序的染色质免疫沉淀（Chromatin immuno-precipitation，ChIP）实验，用于绘制由基因组DNA-RNA杂合体积累所诱导的DNA损伤位点。