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NRSF mediated epigenetic mechanisms of ion channel dysfunction in experimental temporal lobe epilepsy

ChEBI2014-08-12 更新2026-07-21 收录

癫痫发病机制

离子通道表观遗传调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-22899 数据链接链接失效反馈

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NRSF mediated epigenetic mechanisms of ion channel dysfunction in experimental temporal lobe epilepsy

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创建时间：

2014-08-12

癫痫发病机制

抗癫痫药物靶点

This study was undertaken to assay the effect of lovastatin on the glycogen synthase kinase-3 beta (GSK-3β) and collapsin responsive mediator protein-2 (CRMP-2) signaling pathway and mossy fiber sprou

Figshare2016-01-19 更新50

Quantitative analysis of hippocampal transcriptomes of naÃ¯ve and post-status epilepticus (SE) mouse with or without levetiracetam (LEV).

癫痫发病机制

药物作用机制

LEV is known to be involved in neuroprotection via anti-angiogenesis and anti-inflammatory activities against blood-brain barrier dysfunction in the acute phase of epileptogenesis after SE, but the me

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Data_Sheet_1_Mild Inactivation of RE-1 Silencing Transcription Factor (REST) Reduces Susceptibility to Kainic Acid-Induced Seizures.docx

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神经基因调控

RE-1 Silencing Transcription factor (REST) controls several steps in neural development by modulating the expression of a wide range of neural genes. Alterations in REST expression have been associate

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Additional file 6 of Transcriptomic profiling of high- and low-spiking regions reveals novel epileptogenic mechanisms in focal cortical dysplasia type II patients

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转录组学分析

Additional file 6. List of common genes found significantly altered in all three softwares.

NIAID Data Ecosystem40

Temporal analysis of P15 hippocampus in kainate-induced seizures. Koh-2K08NS002068-04. Rattus norvegicus

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基因表达

Early childhood convulsions have been correlated with hippocampal neuron loss in patients with intractable temporal lobe epilepsy. Using a "two-hit" rat seizure model, we have shown that animals subje

NIAID Data Ecosystem30

NRSF mediated epigenetic mechanisms of ion channel dysfunction in experimental temporal lobe epilepsy

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