TET1 KO affects Sox9 function [methylation]

NIAID Data Ecosystem2026-04-25 收录

胚胎软骨发育

DNA甲基化分析

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https://www.ncbi.nlm.nih.gov/sra/SRP120336 数据链接链接失效反馈

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We report that TET1 mediated 5hmC deposition is necessary for Sox9 function in embryonic cartilage development. Overall design: 5hmC and 5mC was profiled in progenitor, intermediate and mature ATDC5 differentiation.

创建时间：

2020-11-06

RRBS Deer Mice Hypoxia

表观遗传学

DNA甲基化分析

We provide RRBS data from left ventricle tissue of lowland and highland mice exposed to hypoxic and normal oxygen (i.e. normoxic) chambers. These data help us understand whether population-specific ev

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Natural depletion of H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation

转座子调控

DNA甲基化分析

Transposable elements (TEs) are largely inactive. Interestingly, a subset of TEs are naturally expressed in the vegetative cell (VC) of the male gametophyte, pollen in Arabidopsis. However, the extent

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Clinical and molecular risk factors in extracranial malignanat rhabdoid tumors - towards an integrated model of high-risk tumors

恶性横纹肌样瘤预后预测

DNA甲基化分析

We characterize relapse patterns in eMRT and analyzed DNA methylation of eMRT primary and relapse tissues. Using NMF-based clustering, we identify 3 subgroups of which ne subgroup displayed significan

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TET1 KO affects Sox9 function [growth plate tissue]

胚胎软骨发育

TET1介导表观遗传调控

We report that TET1 mediated 5hmC deposition is necessary for Sox9 function in embryonic cartilage development Overall design: We examine the transcriptional changes after TET1 KO in E17.5 mouse chond

NIAID Data Ecosystem10

MBD-Seq was applied to study the CpG methylation map of immortallyzed human myoblasts after DiPRO1/ZNF555 inhibition. MBD-Seq was applied to study the CpG methylation map of immortallyzed human myoblasts after DiPRO1/ZNF555 inhibition

DNA甲基化分析

ZNF555基因功能

The methylation enrichment was determined by MIRA-sequencing after MBD2-capture using the MethylCollector™ Ultra Kit (Active Motif) performed on DNA samples derived from immortallized human myoblasts.

NIAID Data Ecosystem00

TET1 KO affects Sox9 function [methylation]

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