Dataset for the project "Emotional dysregulation in adolescents: clinical and biological correlates" Italian Ministry of Health, Ricerca Finalizzata (GR-2018-12366754)

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Dataset for the project “Emotional dysregulation in adolescents: clinical and biological correlates”, Italian Ministry of Health, Ricerca Finalizzata (GR-2018-12366754) 

Specific Aim 1: To analyze the level of emotional dysregulation (ED) in two samples of adolescents (a community sample of adolescent students; a clinical sample of adolescent patients) and to assess the association between ED, clinical and social variables by comparing subgroups of adolescents showing different levels of ED.

Specific Aim: 1.1: To evaluate the level of ED and clinical variables before and after the pandemic on a sample of adolescent students.

Specific Aim 2: To investigate whether alterations in biological features related to stress response and inflammation can underlie ED and the vulnerability for psychopathology.

Specific Aim 3: To assess the outcomes of a brief psychoeducational interventions for adolescent students by evaluating change in maladaptive behaviors and emotional regulation skills.

The present dataset contains the following four folders: 

        Folder Rawdata_Aim1 [Unpublished Data]: it includes two files:

·        File DB_aim1_students.sav: a dataset containing in the first column the sample ID the following rawdata:

→   Demographic data

→   Health-related data

→   Lifestyle habits

→   Social context

→   Academic functioning

→   Difficulties in Emotion Regulation Scale

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills

→   Personality Inventory

→   Emotion Regulation Questionnaire

→   Toronto Alexythymia Scale

→   State-Trait Anger Expression Inventory

→   Screen for Child Anxiety Related Emotional Disorders

→   Barratt Impulsiveness Scale

→   Patient Health Questionnaire

→   Childhood Trauma Questionnaire

→   Strengths and Difficulties Questionnaire

·        File DB_aim1_patients.sav: a dataset containing in the first column the sample ID and the following rawdata

→   Demographic data

→   Health-related data

→   Lifestyle habits

→   Social context

→   Academic functioning

→   Difficulties in Emotion Regulation Scale

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills

→   Personality Inventory

→   Emotion Regulation Questionnaire

→   Toronto Alexythymia Scale

→   State-Trait Anger Expression Inventory

→   Screen for Child Anxiety Related Emotional Disorders

→   Barratt Impulsiveness Scale

→   Patient Health Questionnaire

→   Childhood Trauma Questionnaire

→   Strengths and Difficulties Questionnaire

    Folder Rawdata_Aim1.1 [published Data]

Results from aim 1.1 are published in:

Pedrini, L., Meloni, S., Lanfredi, M., Ferrari, C., Geviti, A., Cattaneo, A., & Rossi, R. (2022). Adolescents' mental health and maladaptive behaviors before the Covid-19 pandemic and 1-year after: analysis of trajectories over time and associated factors. Child and adolescent psychiatry and mental health, 16(1), 42.

Pedrini, L., Meloni, S., Dawson, J., Geviti, A., Bonfiglio, N. S., Cattaneo, A., & Rossi, R. (2024). The Associations between Lifestyle Habits and Anxiety: A Prospective Study on Adolescents One Year after the Outbreak of the COVID-19 Pandemic. Children (Basel, Switzerland), 11(3), 282.

The folder Rawdata_Aim1.1 includes the following file:

·        File DB_ PrePost pandemic.sav: a dataset containing in the first column the sample ID and the following rawdata

→   Demographic data

→   Lifestyle habits at T0

→   Lifestyle habits at T1

→   Social context variables

→   Experience during lockdown

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T0

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T1

→   Difficulties in Emotion regulation Regulation Scale at T0

→   Difficulties in Emotion regulation Regulation Scale at T1

→   Screen for Child Anxiety Related Emotional Disorders at T0

→   Screen for Child Anxiety Related Emotional Disorders at T1

→   Barratt Impulsiveness Scale at T0

→   Barratt Impulsiveness Scale at T1

→   Patient Health Questionnaire at T0

→   Patient Health Questionnaire at T1   

     Folder Rawdata_Aim2 [Unpublished Data]:

·        Rawdata_Aim2: A dataset (folder) containing the following excel files:

-        Rawdata_GeneExpression:  An excel file containing in the first column the sample ID and in the following columns output of gene expression analyses (one column for each gene):

→   GAPDH

→   FKBP5  

→   NR3C1 

→   SGK1    

→   FOXO1 

→   MIF      

→   TNF      

→   CLOCK 

→   IL6        

→   IL10     

→   IL13Ra 

→   IL6ST   

→   NLRP3 

→   PER2    

→   TSC22D3            

→   RGS2    

→   IL1B     

→   UBC     

→   DISC1  

→   CXCL10

→   DUSP1 

→   P2RX7  

→   IL18     

→   CRY2    

→   IL1RN  

→   TNFRSF1B         

→   TNFRSF1A         

→   CCL20  

→   CDNF   

→   CXCL8  

→   EIF4a2 

→   CCL2    

→   HLA_DQA1        

→   ITGAM 

→   JAK2     

→   MECP2

→   NFE2L2

→   PNRP   

→   S100a10            

→   STAT1   

→   SATB1  

→   TGFB1  

→   WDR12              

→   NCOA3

→   SIRT1   

→   PPARa  

→   NCOR1

→   NCOR2

→   MT2A  

→   CD68   

→   CD40   

→   CD14   

→   BMPR2

→   BCL2    

→   BAX      

→   A2M     

→   AIF1L   

→   BDNF ISO VI-IX

→   IGF1R  

→   IRF7     

→   NOS     

→   PICK1   

→   COX20

-        Rawdata_ProteinExpression: An excel file containing two worksheets:

→   RawValues IMMUNE-Luminex assay, listing sample ID (Col. A) and Proteins Concentration Values (Col. B – Col. V);

→   RawValues CORTISOL -ELISA assay, listing sample ID (Col. A) and Cortisol Concentration Values at three distinct times of the day (Col. B – Col. D).

Ø  Folder Rawdata_Aim3 [Unpublished Data]: it includes the following file:

·        File DB_aim3.sav: a dataset containing in the first column the sample ID and the following rawdata:

→   sociodemographic data

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T0

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T1

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T3

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T6

→   Social Problem-Solving Inventory-Revised Short Form at T0

→   Social Problem-Solving Inventory-Revised Short Form at T1

→   Social Problem-Solving Inventory-Revised Short Form at T3

→   Social Problem-Solving Inventory-Revised Short Form   at T6

→   Psychological Well-being Scale at T0

→   Psychological Well-being Scale at T1

→   Psychological Well-being Scale at T3

→   Psychological Well-being Scale at T6