Effective dose of methacholine (mg/kg) required to induce a 250% increase of airway resistance.
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aInhalation, b Intranasal *p<0.05 compared to vehicle-treated OVA-sensitized mice. ASM-024 administered by intranasal or inhalation routes immediately prior to the methacholine challenge to OVA-sensitized mice attenuated airway hyper-responsiveness.
创建时间：
2014-01-22
