Understanding prostate cancer onset and progression in order to rationally treat this disease has been critically limited by a dire lack of relevant pre-clinical animal models. We have generated a set

NIAID Data Ecosystem50

Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation. Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

前列腺癌动物模型

放疗响应研究

This study presents a novel allograft model of high-risk, localised PCa. In characterising this model we have focused on its response to radiotherapy (RT). Overall design: The DVL3 cell line was deriv

NIAID Data Ecosystem30

RNA seq analysis of primary tumors and metastases from the NPK (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) prostate cancer mouse model. RNA seq analysis of primary tumors and metastases from the NPK (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) prostate cancer mouse model

前列腺癌动物模型

肿瘤转录组学

Transcriptome analysis of lineage-marked prostate primary tumors and metastases from the NPK mouse model (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) Overall design: Male mice

NIAID Data Ecosystem60

AKT_Prostate_RAD001_v_PLACEBO. Mus musculus

前列腺癌动物模型

mTOR抑制剂效应

Transgenic (Probasin driven Myr-AKT)or wild-type littermates were treated with RAD001 or placebo and sacrificed at 12 and 48 hours following the beginning of treatment Keywords = AKT Prostate RAD001 m

NIAID Data Ecosystem40

Effect of weekly Salmonella dosages on prostate tumor development in the 5 month TRAMP prostate.

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