Transcriptomic analysis of epithelial to mesenchymal transition in EGFR-mutant NSCLC cell lines.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE123031
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资源简介：
We have employed a transcriptomic approach to find a molecular target that could compensate for the loss of EGFR signaling in NSCLC cell lines with acquired resistance to EGFR TKIs with an EMT phenotype. Total RNA obtained from EGFR-mutant HCC827 lung adenocarcinoma cells treated with TGFB1 (10 ng/mL, 72h), infected with lentiviruses encoding shRNA against epithelial CDH1, or overexpressing the EMT transcription factor SNAIL.
创建时间：
2020-01-01
