DDX3X Induces Primary EGFR-TKI Resistance Based on Intratumor Heterogeneity in Lung Cancer Cells Harboring EGFR-Activating Mutations - Figure 7

A. MTT assays were used to determine the proliferation of adherent and nonadherent PC9 cells, as well as R-PC9 cells, which were obtained by long-term exposure to increasing concentrations of erlotinib. Data are presented as the mean ± SD. Samples were prepared in triplicate. * indicates significant differences by two-way ANOVA and ad hoc analysis. B. Immunoblotting analysis of DDX3X expression in parental PC9 cells and R-PC9 cells.