Central nervous system-associated macrophages modulate the immune response following stroke in aged mice

To study the differential role of central nervous system-associated macrophages (CAMs) in neuroinflammation after stroke between young and aged mice, we FACS sorted CD3-CD11b+CD45+CD206+ CAMs from brains of C57BL/6 mice aged 2 months (young) and 18 months (old) Comparative gene expression profiling analysis of RNA-seq data for CNS-associated macrophages from C57BL/6 mice aged 2 months (young) or 18 months (aged)