NKX2-1 transcription factor binding site (TFBS) analysis. First, we used HOMER to identify predicted NKX2-1 binding sites (using the HOMER built in matrix “nkx2.1.motif”) across the GRCh38 genome, and
Motif discovery is essential for deciphering regulatory codes from high throughput genomic data, such as those from ChIP-chip/seq experiments. However, there remains a lack of effective and efficient
The histone variant H2A.Z is central to early embryonic development, determining transcriptional competency through chromatin regulation of gene promoters and enhancers. In addition to genic loci, we