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Rapamycin effect on gene expression: dependence on c-Myc. Rattus norvegicus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA121183
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This experiment utilized rat fibroblasts that are wild-type for c-Myc (TGR-1 cells) and null for c-Myc (HO15.19 cells). Both were treated treated with rapamycin for 24 hr (comparison group, vehicle control). Overall design: Cells were studied under conditions that supported proliferation. Rapamycin (50nM or DMSO vehicle control) was added for 24 hr after which RNA was prepared and analyzed.
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2010-10-25
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