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Thio-Michael–Aldol–Cyclization Cascade of N-Enoyl Thiazolidinethiones with Aliphatic Aldehydes and Cyclic Ketones

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DataCite Commons2020-08-19 更新2024-07-13 收录
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1340817
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资源简介:
A thio-Michael–aldol–cyclization cascade reaction of N-enoyl thiazolidinethiones with aliphatic aldehydes and cyclic ­ketones was promoted by Ti(IV) chloride to deliver highly complex tricyclic adducts possessing a carbon atom tetrasubstituted with ­heteroatoms and up to four stereogenic centers in good to very good yields.
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© Georg Thieme Verlag
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2015-04-22
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