Summary of the performance of classifiers.

CC: Classifier using CRP only in the initial cohort. CE: Classifiers using two or more eCRF variables (incl. CRP) in the initial cohort. CEM: Classifiers using all input eCRF variables (incl. CRP) and at least one nasal cavity microbiota variable in the initial cohort. CC*: Classifier using only CRP in the 5-fold cross-validation of the expanded cohort. CEM*: Classifiers using two or more variables (regardless of eCRF or nasal cavity microbiota origin) in the 5-fold cross-validation of the expanded cohort. CCM*: Classifier using CRP plus all 7 microbiota genera variables in the 5-fold cross-validation of the expanded cohort. AUC: Area Under the ROC Curve. SEM: standard error of the mean. (XLSX)