DHODH in complex with Ligand 10
收藏Protein Data Bank Japan2024-07-24 更新2026-06-30 收录
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https://pdbj.org/mine/summary/9bkm
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资源简介：
DHODH in complex with Ligand 10 Descriptor: (2M,6P)-2-(2-chloro-6-fluorophenyl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-7-fluoro-4-(propan-2-yl)isoquinolin-1(2H)-one, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... Authors: Shaffer, P.L. Deposit date: 2024-04-29 Release date: 2024-07-03 Last modified: 2024-07-24 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML. J.Med.Chem., 67, 2024
创建时间：
2024-04-29
