Investigation of the role of PRL-3 in leukemogenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE64872
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In order to investigate the role of PRL-3 in the leukemogenesis, we transfected a control vector (pEGFP) and (human) PRL-3 gene into an acute myeloid leukemia (AML) cell line TF-1, respectively. After drug selection and FACS sorting, we established TF1-pEGFP and TF1-hPRL-3 isogenic cell lines. In vitro and in vivo experiments were conducted to characterized this pair of isogenic cell lines. Results provided insight into the molecular basis of PRL-3 in contributing the development of AML. Whole genome microarray comparsion of TF1-pEGFP vs TF1-hPRL-3 cell line
创建时间：
2018-07-26
