Data from: Cost of reproduction in the Queensland fruit fly: Y-model vs. lethal protein hypothesis

The trade-off between lifespan and reproduction is commonly explained by differential allocation of limited resources. Recent research has shown that the ratio of protein to carbohydrate (P:C) of a fly's diet mediates the lifespan/reproduction trade-off, with higher P:C diets increasing egg production but decreasing lifespan. To test if this P:C effect is due to changing allocation strategies (Y-model hypothesis) or detrimental effects of protein ingestion on lifespan (lethal protein hypothesis), we measured lifespan and egg production in Queensland fruit flies varying in reproductive status (mated, virgin, and sterilized females, virgin males) that were fed one of 18 diets varying in protein and carbohydrate amounts. The Y-model predicts that for sterilized females and for males, which require little protein for reproduction, there will be no effect of P:C ratio on lifespan; the lethal protein hypothesis predicts that the effect of P:C ratio should be similar in all groups. In support of the lethal protein hypothesis, and counter to the Y model, the P:C ratio of the ingested diets had similar effects for all groups. We conclude that the trade-off between lifespan and reproduction is mediated by the detrimental side-effects of protein ingestion on lifespan.

Usage Notes
Egg rate dataThis file contains the egg rate data for virgin and mated females.egg_data.csvlifespan_dataThis file contains lifespan data.

寿命与繁殖之间的权衡通常被解释为对有限资源的不同分配策略。近期的研究表明，果蝇饮食中蛋白质与碳水化合物的比例（P:C）调节了寿命与繁殖之间的权衡，较高的P:C比例饮食能够增加卵的产出但降低寿命。为了检验这种P:C效应是由于分配策略的变化（Y模型假设）还是蛋白质摄入对寿命的损害性影响（致死蛋白质假设），我们对昆士兰果蝇进行了寿命和卵产量的测量，这些果蝇在繁殖状态上存在差异（交配、未交配以及绝育的雌性，未交配的雄性），并分别给予18种不同蛋白质和碳水化合物含量的饮食。Y模型预测，对于需要少量蛋白质进行繁殖的绝育雌性和雄性，P:C比例对寿命不会有影响；致死蛋白质假设预测，P:C比例对所有组别的影响应当相似。支持致死蛋白质假设，与Y模型相悖的是，摄入的饮食中的P:C比例对所有组别产生了类似的影响。我们得出结论，寿命与繁殖之间的权衡是由蛋白质摄入对寿命的损害性副作用所调节。

使用说明
卵率数据
此文件包含未交配和交配的雌性的卵率数据。
lifespan_data
此文件包含寿命数据。