Gene expression signatures for highly effective dermal sheath cup cells

In order to identify genes that correlate with efficacy in clinical trials, titled Autologous cell–based therapy for male and female pattern hair loss using dermal sheath cup cells, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish efficacy. RNA was extracted from each DSC-cells that was used in the clinical trial, and gene expression profiling by microarrays was performed. DSC cells derived from representative 8 IDs of highly effective and less effecgive group were analyzed. Signature was identified that distinguished between highly and less effective IDs. Gene expression was measured in dermal sheath cup cells derived from 8 highly or less effective individuals.