Relative fitness expressed as competition indexes (CI) and frequency of different resistant mutants isolated at the different time points.
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CIs were determined as described in Materials and Methods.aNumbers are averages based on two independent measurements (shown within parantheses).bFrequency indicates how many of the 10 sub-clones obtained from that particular time point and isolate carried the specified resistance mutation.
创建时间：
2015-12-02
