SM4 - miRNAs common between obesity and AD.xlsx

To cover all miRNAs likely to be involved in metabolic disorders common to AD and obesity, another database was accessed, in which it is possible to insert search terms. Thus, The Human microRNA Disease Database (HMDD) v4.0 (Cui et al., 2024) was used to access miRNA sequences via disease descriptors (‘obesity’ and ‘Alzheimer’s disease’), allowing the identification of miRNAs related to obesity and Alzheimer’s disease in a general manner. There were 422 miRNAs related to obesity and 779 to Alzheimer's disease; these two lists were overlapped, and we were able to identify 113 of them that were common between both conditions (Supplementary Material 4).