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Crystal structure of M. tuberculosis InhA inhibited by PT506

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of M. tuberculosis InhA inhibited by PT506 Descriptor: 2-[4-[(4-cyclopropyl-1,2,3-triazol-1-yl)methyl]-2-oxidanyl-phenoxy]benzenecarbonitrile, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. Deposit date: 2017-01-10 Release date: 2017-02-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017

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2017-01-10
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