Candidate indels with predicted functional impact on HuR binding.

This table lists natural human indels predicted to have a physiologically significant impact () on the binding affinity of the HuR protein. The columns are as follows: chromosome, the chromosome on which the indel is located; indel_genomic_coordinate, the genomic coordinate (GRCh38) of the first nucleotide of the indel on the reference allele; dbSNP_ID, the reference SNP ID for the indel from the dbSNP database; ref_allele, the reference allele sequence; alt_allele, the alternate allele sequence; binding_site_locus, the genomic coordinates of the computationally determined 7-nucleotide HuR binding site; binding_region_locus, the genomic coordinates of the experimentally determined 25-nucleotide region from which the binding site was identified; delta_delta_G, the predicted change in binding preference in kcal/mol, where a positive value indicates stronger binding to the shorter allele; transcript_ids, a semicolon-separated list of Ensembl transcript IDs that overlap the indel’s location. (XLS)