EP400 is required for Max and MCPyV mediated gene activation. Homo sapiens

To determine if EP400 knockdown would affect Max target genes in Merkel cell carcinoma cell line MKL-1, we performed RNA-seq analyses of MKL-1 cells inducibly expressing EP400 shRNA and compared to ChIP-seq data using BETA analyses. Overall design: EP400 was inducibly reduced with shRNA in MKL-1 cells to analyze gene regulation.