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Crystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor Descriptor: 7-bromanyl-3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Harrison, T, Gavory, G, O'Dowd, C, Helm, M, Flasz, I, Arkoudis, E, Dossang, A, Hughes, C, Cassidy, E, McClelland, K, Odrzywol, E, Page, N, Barker, O, Miel, H. Deposit date: 2017-02-27 Release date: 2017-12-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Discovery and characterization of highly potent and selective allosteric USP7 inhibitors. Nat. Chem. Biol., 14, 2018
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2017-02-27
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