REFERENCE DATASET: Expression of 97 surface markers and 462 mRNAs in 49057 cells from healthy young and healthy old bone marrow

Seurat v3 object<b><br></b><b>ASSAYS</b>:AB: Antibody expression dataRNA: mRNA expression dataBOTH: mRNA and Antibody expression data, concatenatedintegrated: Antibody and mRNA expression matrices were concatenated and data was integrated across patients using scanorama<br><b>DIMENSIONALITY REDUCTION</b><b>MOFAUMAP</b>: UMAP performed on MOFA dimensions. Display used in the manuscript. Set reduction="MOFAUMAP"in most cases!<br>ProjectedMOFA: Multi-OMICS factor analysis to integrate AB and RNA data. MOFA was run on scanorama-integrated data and served as input for clustering and further dimensionality reduction.MOFATSNE: UMAP performed on MOFA dimensions.<br><br><b>METADATA</b>Batch: Source individual (BM1-3, Aged1-3).class: Type of individual (healthy young, healthy old).<br><b>Change log: </b>Compared to the previous version of this file, the 3 AML patients were removed. A new object with 15 AML patients has been created: https://doi.org/10.6084/m9.figshare.14780127.v1<br>