CDK5:p25 translocates to the nucleus
收藏reactome.org2025-03-25 收录
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The complex of CDK5 and p25 can translocate to the nucleus (Patrick et al. 1999). Nuclear envelope fragmentation, initiated by CDK5:p25-mediate phosphorylation of lamin A and B1, increases access of the CDK5:p25 complex to nuclear proteins (Chang et al. 2011).
CDK5与p25的复合物可迁移至细胞核(参见Patrick等,1999年研究)。由CDK5:p25介导的层蛋白A和B1的磷酸化引发的核被膜裂解,提升了CDK5:p25复合物对核蛋白的访问性(参见Chang等,2011年研究)。
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