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RNA-Seq analysis of human Tr1, Tregs and IL10neg cells

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https://www.ncbi.nlm.nih.gov/sra/SRP181623
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To determine the differentially expressed genes between these subsets and identify the core human in vivo differentiated Tr1 cell gene signature Overall design: Human Tr1 and IL-10 neg cells were sorted using an IL-10capture assay following 16h CD3/CD28 bead activation, matched Tregs were sorted from unstimulated cells then activated by CD3/CD28 beads for 16h. Samples are from 3 donors from 3 independent experiments (HIF037, HIF038 and HIF039).
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2019-09-23
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