CTL differentiation: WT vs. IL-2Ra deficient CTL

Gene expression analysis of WT and IL-2Ra-deficient CTL (P14) isolated 8 days after inffection with LCMV. The goals of the study are to assess the impact of IL-2 signals on effector and memory CTL differentiation. This is a 2-condition experiement comparing WT P14 Tg T cells eight days after LCMV infection to IL-2Ra-deficient P14 Tg T cells isolated at the same time from the same host. Cells are isolated via FACS-sorting form the spleen.