norven

The data presented herein relates to the article entitled "Effects of norfluoxetine and venlafaxine in zebrafish larvae: molecular data" by Rodrigues et al., submitted to Data In Brief. The file contains raw data corresponding to expression of several zebrafish genes related to mode of action of psychoactive compounds acting upon serotonergic or/and noradrenergic neurotransmission. Zebrafish embryos were exposed to concentrations of norfluoxetine (0.64 to 400 ng/L), venlafaxine (16 to 10000 ng/L) or their combination (3.2 ng/L norfluoxetine + 2000 ng/L venlafaxine) over 80 hpf (hours post-fertilisation). At the end of the exposure, larvae were collected for quantification of the expression of 34 genes. Gene expression was evaluated by qPCR (SYBRGreen). Details on exposure conditions, gene sequences, primers employed and assay conditions are provided in the submitted article. The work was supported by funding EU and FCT/UEFISCDI/FORMAS funding through project REWATER (ERA-NET Cofund WaterWorks2015, Water JPI) and by national funds through FCT (Portuguese Foundation for the Science and Technology) within the scope of UIDB/04423/2020 and UIDP/04423/2020. PR was supported by a PhD fellowship (SFRH/BD/134518/2017) from FCT.