Comparison of mass spectrometry and Fourier transform infrared spectroscopy of plasma samples in identification of patients with fracture-related infections

<p style="margin-bottom:11px"><span style="font-size:12pt"><span style="line-height:115%"><span aptos="" style="font-family:">This dataset contains raw data on protein abundances obtained through mass spectrometry (MS) and absorbance spectra from Fourier transform infrared (FTIR) spectroscopy of dried film plasma samples. Samples were collected from patients who developed fracture-related infections following surgical repair with implants and from matched patients who did not experience postoperative infection. Patients were paired based on age, gender, and body mass index to create a balanced cohort. The purpose of this publication is to provide open access to the de-identified raw data that underlines the results reported in our related study published in <i>PLOS ONE</i>.</span></span></span></p>

<p style="margin-bottom:11px"><span style="font-size:12pt"><span style="line-height:115%"><span aptos="" style="font-family:">The raw data is provided in an excel sheet for the MS data (</span></span></span>abundance ratios of each of the 1058 protein components identified). Sample IDs for each sample are C (control)/ FRI (fracture-related infection)_numerical ID (XXXX). The patients were matched in pairs based on age, gender and body mass index as much as possible listing them as pairs by assigning each pair a number from 1-13 for FRI and Controls.The raw spectra obtained from FTIR spectroscopy are provided as individual spectra files in the folder titled "FTIR raw data". Each file is identified based on the sample ID: C(control)/FRI (fracture-related infection)_ID that matches the sample ID in the spreadsheet (numerical value XXXX)_well location on the microplate (A-H and 1-12 based ID). Each sample has three replicates that are distinguishable base on the well location on the ID. Each matlab file for the spectra has <span class="notice-text">the following data AB (absorption), ScRf (control spectra), and ScSm (sample spectra). Within each of these, the first column is absorption and the second column is wave number.</span></p>