Supplementary Materials for Respiratory Syncytial Virus Genetic Diversity and Lineage Changes in Ireland pre- and post-COVID-19 pandemic

The datasets presented here are the list of publicly available reference sequences used in NextClade (https://github.com/rsv-lineages) to provide the lineage classification of samples and used as reference for analysis of Irish RSV sequences (Supplementary Table 1), the list of sequenced Human respiratory syncytial viruses (RSV) in the Republic of Ireland during the period 2015-2024 (Supplementary Table 2) and the details of sequences downloaded from GISAID corresponding to European RSV sequences for the same period of time.

Description of the data and file structure

The files in this dataset were formatted in Microsoft Excel 2019 to allow easy access and manipulation of the data. The data corresponds to details on the sequences used in the analysis of RSV in Europe during the 2015-2024 period. The contents of the files are described below: -Supplementary Table 1: NextClade Reference Sequences publicly available at https://github.com/rsv-lineages. -Supplementary Table 2: Irish RSV Sequence Details contains details on the sequences generated in our study with the GenBank accession number, the GISAID accession number, reported collection RSV season, Nextclade assigned taxonomical clade. -Supplementary Table 3: European RSV Sequence Details contains a list of European RSV sequences downloaded from GISAID (https://gisaid.org/) with details on the sampling RSV season, the accession number, country of collection, and lineage assigned by NextClade.

Sharing/Access information

The databases used to extract and deposit the data were:

-GenBank: the North American repository of sequences and publicly available at: https://www.ncbi.nlm.nih.gov/genbank/ 

-GISAID:International consortium of sequences with some metadata and clinical data. It is a semi-public repository with easy access requiring only to create an account. Available at: https://gisaid.org/

-Github: reference sequences of RSV are available at the repository https://github.com/