Lower motor neuron transcriptomic analysis of a TDP-43 Q331K knock-in mouse

Here we analyse transcriptome profiles from laser captured lower motor neurons between wild type, heterozygous and homozygous TDP-43 Q331K knockin mice. Transcriptome (RNA-Seq) from 5 month old laser captured lower motor neurons本研究分析了野生型（wild type）、杂合子（heterozygous）与纯合子（homozygous）TDP-43 Q331K敲入（knockin）小鼠的激光捕获下运动神经元（laser captured lower motor neurons）的转录组谱。本研究通过RNA测序（RNA-Seq）获取转录组数据，所用样本为5月龄小鼠的上述激光捕获下运动神经元。