Transcriptome data of MHCII-high and MHCII-low hematopoietic stem cells of middle-aged mice. Transcriptome data of MHCII-high and MHCII-low hematopoietic stem cells of middle-aged mice

Analysis of MHCII-high (MHCII-hi) and MHCII-low (MHCII-lo) hematopoietic stem cells (Lineage-Sca-1+c-Kit+CD150+Flt3-CD48-). The two population of hematopoietic stem cell (HSC) were purified from the bone marrow of 12 months old (12 mo) mice. Results provide insight into the role of MHCII in HSC. Overall design: We then performed gene expression profiling analysis using data obtained from RNA-seq of MHCII-hi and MHCII-lo HSCs of mice at 12 mo.