ImmGen ULI: Male-Female Immune Differences

Primary RNA Seq data for 11 diverse immunocyte populations from male and female mice of varying ages stimulated with different dose of IFN and sequenced using ImmGen's standard ultra-low input RNA-seq pipeline RNASeq data for 11 cell populations from male and female mice generated by ImmGen labs to study sexual differences in the immune system (companion ATACseq datasets are found in GSE100738). These mice comprised of varying ages, including 6-8weeks and 2- 20months old. In addition, mice were stimulated with 1K and 10K Type 1 interferon to understand sex specific responses. contributor: Immunological Genome Project Consortium本数据集包含两类RNA测序（RNA-seq）数据：其一为经不同剂量干扰素（IFN）刺激、采用免疫基因组计划（ImmGen）标准超低起始量RNA测序流程完成测序的、来自不同年龄雌雄小鼠的11种免疫细胞群体的原始RNA测序数据；其二为免疫基因组计划（ImmGen）实验室为研究免疫系统性别差异所构建的雌雄小鼠11种细胞群体的RNA测序数据，配套的转座酶可及性测序（ATAC-seq）数据集收录于GSE100738。实验所用小鼠的年龄跨度广泛，包含6-8周龄与2至20月龄个体。此外，实验中以1K和10K剂量的I型干扰素对小鼠进行刺激，以探究其性别特异性免疫应答。贡献方：免疫基因组计划联盟（Immunological Genome Project Consortium）