five

Pathways associated with 5-FU resistance.

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Figshare2015-12-02 更新2026-04-29 收录
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KEGG pathway analysis was used to identify pathways from 5-FU in vitro genelists and the pathways common to all genelists were selected. The 5-FU in vitro genelists were: (1) genes induced by 5-FU in the sensitive HCT116 parentals (inducible parental), (2) genes induced by 5-FU in the 5-FU-resistant HCT116 sub-line (inducible resistant) and (3) constitutively de-regulated genes in the 5-FU-resistant sub-line compared to the sensitive parentals (constitutively deregulated). Pathways contained genes passing a 1.5 fold change and t-test (p
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2015-12-02
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