Data from: Prevalence characteristics of cervical human papillomavirus (HPV) genotypes in the Taizhou area, China: a cross-sectional study of 37 967 women from the general population

Objectives: High-risk human papillomaviruses (hrHPVs) are highly prevalent
worldwide, and HPV genotypes differ between geographical regions; however,
sexually transmitted HPV may lead to cervical carcinogenesis. The
objective of this cross-sectional study was to estimate the prevalence
characteristics of cervical HPV genotypes in Taizhou, Southeast China.
Setting and participants: A population-based sample of 37 967 eligible
women (median age: 41.6; range: 15–90 years) visiting the Taizhou ENZE
Medical Center in Taizhou (2012–2016) was analysed. HPV genotyping was
performed on the collected specimens using a GP5+/bioGP6+-PCR/MPG assay by
Luminex 200, which simultaneously identifies 27 different HPV genotypes
and the β-globin gene (internal control). Results: The overall HPV
infection rate was 22.8% in the Taizhou-based population, and the
prevalence of high-risk HPV, low-risk HPV and mixed high-risk and low-risk
HPV infection was 14.2%, 5.7% and 3.0%, respectively. The most prevalent
genotypes were HPV52 (19.7%), 16 (11.9%), 58 (11.5%), 39 (7.2%), 18 (6.6%)
and 56 (5.6%). The rate of multiple-type HPV infection was 5.7% in the
whole population, and the HPV52+58, HPV16+52 and HPV16+18 mixed genotypes
were most common in women with multiple infections. The age-specific HPV
prevalence showed a bimodal curve, with a first peak below the age of 21
years (41.6%), followed by a second peak in the age group of 56–60 years
(28.5%). Moreover, the HPV infection rate differed significantly between
the outpatient and physical examination groups (24.0% vs 19.5%,
p<0.0001). Further data comparisons showed that the distribution of
HPV genotypes varied markedly between the two groups. Conclusions: Data
from this study could be valuable for HPV-based cervical cancer screening
efforts in certain areas, support the local vaccination programme in the
Taizhou region and facilitate future diagnosis and treatment of HPV
diseases.