Differentiated human NPCs were exposed to 5 ng/ml of IL-1β or TNF-α in the absence or presence of 15 µM of Bay 11-7085, NF-kB inhibitor (Bay) or 1 µM of JAK inhibitor (JI) to block STAT-1 activation.
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https://figshare.com/articles/dataset/_Differentiated_human_NPCs_were_exposed_to_5_ng_ml_of_IL_1_946_or_TNF_945_in_the_absence_or_presence_of_15_181_M_of_Bay_11_7085_NF_kB_inhibitor_Bay_or_1_181_M_of_JAK_inhibitor_JI_to_block_STAT_1_activation_/757928
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资源简介：
Induction of cytokines and chemokines by IL-1β and TNF-α involves activation of NF-kB and STAT-1 (Mean fold induction).
Cells were also exposed to a combination of IL-1β and TNF-α. After 18 h, the neurons were processed for RNA isolation and custom-made Taqman low density array (TLDA). Values represent mean fold induction over untreated control from four independent arrays. Cytokine-mediated induction of inflammatory mediators involved activation of STAT-1 and NF-kB.
*Synergistic induction by IL-1β and TNF-α.
创建时间：
2013-07-29
