Structure of Nek2 bound to aminopyrazine compound 2
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Structure of Nek2 bound to aminopyrazine compound 2 Descriptor: 1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 Authors: Mas-Droux, C, Bayliss, R. Deposit date: 2010-07-07 Release date: 2010-10-27 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
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2010-07-07
