Tocotrienol as an anti-cancer agent
收藏DataCite Commons2026-03-12 更新2026-05-07 收录
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https://redu.unicamp.br/citation?persistentId=doi:10.25824/redu/PL8XW4
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资源简介：
Therapeutic strategies for acute myeloid leukemia (AML) remain limited by toxicity and suboptimal efficacy, highlighting the need for novel agents with improved safety profiles. AML is an aggressive hematologic malignancy driven by mutations in hematopoietic stem cells (HSCs) or myeloid progenitors that lead to uncontrolled proliferation and accumulation of immature myeloid cells. In this study, we investigated the therapeutic potential of a 70% tocotrienol-enriched fraction isolated from Bixa orellana L. for AML treatment by evaluating its effects on AML cells and in leukemic mouse models.
提供机构：
Repositório de Dados de Pesquisa da Unicamp
创建时间：
2026-03-10
