Persistent alveolar bronchiolization, interstitial fibrosis and impaired lung function post exercise are features of long-COVID-19 in SARS-CoV-2-Delta variant infected aged hamsters

The impact of Covid-19 infection on the hamster lung shortly after infection and up to 112 days was investigated using RNA-Seq to examine both short-term effects and long-term changes in the lung environment. Overall design: The transcriptome of the hamster lung was measured at various time points (1, 3, 6, 14, 28, 56, and 112 days post-infection (dpi)) and compared with the corresponding uninfected mock controls