STK38 is a Key Regulator of MYC Transcriptional Activity in Human B lymphoma cells

ChEBI2012-01-06 更新2026-07-21 收录

B淋巴瘤分子机制

MYC基因调控

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STK38 is a Key Regulator of MYC Transcriptional Activity in Human B lymphoma cells

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2012-01-06

RNA-seq analysis of HeLa cells following MYC inhibition with ASO

转录组分析

MYC基因调控

We performed RNA-seq on HeLa cells treated with MYCASO-3, a non-targeting ASO (NT-ASO), Lipofectamine alone, and untreated cells Overall design: Cells were treated for 4h or 18h with 10 nM ASO (formul

NIAID Data Ecosystem50

Mice deficient of Myc super-enhancer region reveal a differential control mechanism between normal and pathological growth

癌细胞机制

MYC基因调控

The gene desert upstream of the Myc oncogene on chromosome 8q24 contains susceptibility loci for several major forms of human cancer, including cancers of breast, prostate, and colon. The region shows

NIAID Data Ecosystem40

SIRT7 suppresses tumorigenesis by attenuating MYC activity

肿瘤抑制机制

MYC基因调控

SIRT7 is a member of the mammalian sirtuin family of NAD+ dependent deacylases, and interacts with RNA polymerase I and UBF to regulate rDNA transcription. Various studies in mammalian cells and hum

NIAID Data Ecosystem30

Ubiquitin-dependent transfer of PAF1c from MYC onto RNA Polymerase controls double-strand break repair at active promoters [ChIP-seq BI8626]. Ubiquitin-dependent transfer of PAF1c from MYC onto RNA Polymerase controls double-strand break repair at active promoters [ChIP-seq BI8626]

DNA双链断裂修复

MYC基因调控

MYC family proteins are oncogenic transcription factors that can globally affect the function of RNA Polymerase II (RNAPII). The ability of MYC proteins to promote transcription elongation depends on

NIAID Data Ecosystem50

Deep sequencing of MYC DNA-binding sites in Burkitt''s lymphoma

Burkitt淋巴瘤分子机制

MYC基因调控

Background: MYC is a transcription factor encoded by the c-MYC gene (thereafter termed MYC). MYC is key transcription factor involved in many central cellular processes including ribosomal biogenesis.

NIAID Data Ecosystem30

STK38 is a Key Regulator of MYC Transcriptional Activity in Human B lymphoma cells

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