Effects of early intervention with maternal faecal bacteria and antibiotics on liver metabolome and transcription in neonatal pigs

The objective of this study was to investigate the responses of metabolome and transcriptome in the livers of neonatal piglets that were orally inoculated with maternal faecal bacteria suspension and amoxicillin (AM) solution. The results indicate that early intervention with FMT or AM can reduce fatty acid oxidative catabolism and amino acid biosynthesis of neonatal piglets, which provides a reference for regulation host metabolism through early intervention in animal production and even human health.