five

Bulk RNAseq on WT and TKO E14 PGCLCs

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https://www.ncbi.nlm.nih.gov/sra/SRP400258
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We investigate the impact of DNA methylation on epiblast differentiation. To this end, we used in vitro Epiblast-like cell (EpiLC) differentiation on WT and DNA-methylation free TKO murine ESCs. We next performed bulk RNAseq at D0, D2, D4, D6 and D8 of differentiation to study transcriptomic differences. Overall design: Comparison of bulk mRNA sequencing results of WT and TKO ESCs (D0), and D2, D4 and D7 cells during PGCLC differentiation
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2023-10-10
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